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Discover the power of STED microscopy

 

Stimulated emission depletion (STED) microscopy upgrades standard confocal laser scanning microscopy by bypassing the diffraction limit of light and allows to create super-resolution images.

For optimal STED imaging, abberior offers specially optimized fluorescent dyes. abberior STAR ORANGE and STAR RED are the perfect duo for two-color STED imaging using a STED light at 775 nm. Their molecular structure ensures excellent water solubility and enables background-free imaging. Enjoy the benefits of high photostability and brightness with STAR ORANGE and STAR RED.

SYSY antibodies show high specificity and affinity, making them precise and powerful tools for your microscopy analyses. By using specific antibodies directly coupled to STAR dyes you are able to resolve even finest structures. Direct coupling of STAR dyes to primary antibodies enables direct immune fluorescence with increased binding specificity due to reduced blocking of epitopes. Moreover, reduced linkage errors lead to sharper images. 

Elevate your STED microscopy experience further with primary antibodies from SYSY conjugated to abberior STAR dyes.

 
Presynaptic Bassoon labelled with STAR RED and postsynaptic Homer1 labelled with STAR ORANGE

Presynaptic Bassoon labelled with STAR RED and postsynaptic Homer1 labelled with STAR ORANGE show well-separated synaptic structures. Enhanced resolution by STED imaging enabling e.g. automated counting of synapses.

 

Products

Cat. No. Product Description Application Quantity Price Cart
141 111Bassoon, mouse, monoclonal, purified IgG IgG K.O.WB ICC IHC IHC-P DNA-PAINT 100 µg$420.00
160 011Homer1, mouse, monoclonal, purified IgG IgGWB IP ICC ExM DNA-PAINT EM ELISA 100 µg$435.00
188 002MAP2, rabbit, polyclonal, antiserumantiserumWB ICC IHC IHC-P 200 µl$365.00
104 211Synaptobrevin2, mouse, monoclonal, purified IgG IgG K.O. K.D.WB IP ICC IHC IHC-P DNA-PAINT EM ELISA 50 µg$435.00
Result count: 4
 

Homer1

Homer is a scaffolding protein of the post synaptic density (PSD) and enriched at excitatory synapses. The protein binds metabotropic glutamate receptors, TRPC1, proteins of the Shank family and others. By aggregating these proteins into clusters, homer was suggested to organize distinct signalling domains.

Indirect immunostaining of PFA fixed rat hippocampus neurons with mouse anti-Homer1 and rabbit anti-MAP 2

Indirect immunostaining of PFA fixed rat hippocampus neurons with mouse anti-Homer1 (cat. no. 160 011, dilution 1:500, red) and rabbit anti-MAP 2 (cat. no. 188 002, dilution 1:1000, green). Nuclei have been visualized by DAPI staining (blue).

 

Bassoon

Bassoon is a large protein which consists of an N-terminal Zn2+ finger and several piccolo-bassoon homology domains (PBH-domains). It is generally found together with piccolo, a related huge multi-domain protein of the CAZ (cytoskeletal matrix assembled at active zones). Bassoon is a scaffolding element of the presynapse and is also involved in synaptic vesicle cycling.

Indirect immunostaining of a PFA fixed mouse hippocampus section with mouse anti-Bassoon

Indirect immunostaining of a PFA fixed mouse hippocampus section with mouse anti-Bassoon (cat. no. 141 111, dilution 1:500, red). Nuclei have been visualized by DAPI staining (blue).

 

Synaptobrevin2

The active zone-protein Synaptobrevin2, also known as VAMP2, belongs to a family of integral membrane proteins. It is an essential component of the exocytotic fusion machine, related to a larger protein family referred to as v-SNAREs. Next to neurons, low levels of synaptobrevin2 are present in many other tissues where the protein resides on specialized microvesicles.

Indirect immunostaining of a PFA fixed rat hippocampus section with mouse anti-Synaptobrevin2

Indirect immunostaining of a PFA fixed rat hippocampus section with mouse anti-Synaptobrevin2 (cat.no. 104 211, dilution 1:500, green). Nuclei have been visualized by DAPI staining (blue).