Cat. No.: MP2053
Amount: 1
Price:
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ATTO655 label, Sequence: FAST-LB (Long Binding)
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This Massive Photonics DNA-PAINT Neuro-Imaging Kit is ready-to-use for the staining of the scaffolding active zone protein Bassoon using DNA-PAINT (DNA-Point Accumulation for Imaging in Nanoscale Topography). This localization based super-resolution microscopy method employs short, dye-labeled single stranded DNA that transiently binds its complementary sequences, which are attached to target-specific antibodies or nanobodies. Several Massive Photonics DNA-PAINT Neuro-Imaging Kits can be combined for multi-target staining and super-resolution imaging of various neuronal targets achieving visualization of cytoskeleton-associated and synaptic proteins with resolutions below 20 nm.
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| Applications |
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| MASSIVE-AB-FAST anti-Bassoon-ATTO655 |
This kit provides ready-to-use binders for DNA-PAINT imaging of the scaffolding protein Bassoon, which is essential for the organization of the presynaptic active zone and the regulation of neurotransmitter release. Also included are imager strands and buffers for sample preparation and imaging. This kit contains a monoclonal antibody recognizing Bassoon (cat. no. 141 111) that has been preincubated with single-domain antibodies (sdABs) from NanoTag conjugated to FAST-DNA-PAINT sequence F4. |
| Label | ATTO 655 |
| Immunogen | Recombinant protein corresponding to residues near the central region of rat Bassoon |
| Reactivity |
Reacts with: mouse (O88737), rat (O88778). Other species not tested yet. |
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