Tailor-made Antibodies
and Tools for Life Science
quick order | cart
?
|
login
Home|||||Technical Support
Home > Products > 479 003

Kir2.3 antibody - 479 003

Kir2.3 is an inward rectifier potassium channel
Rabbit polyclonal purified antibody
Cat. No.: 479 003
Amount: 50 µg
Price: $375.00
Cat. No. 479 003 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP-staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: not recommended

Western blot (WB); separation of proteins by PAGE and subsequent transfer to a membrane. Detection of target molecules is carried out with antibodies. Some antibodies require special sample preparation steps. For details, please refer to the “Remarks” section.

Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section.

Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section.

Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section.
Immunogen Recombinant protein corresponding to AA 398 to 445 from mouse Kir2.3 (UniProt Id: P52189)
Reactivity Reacts with: mouse (P52189), rat (P52190).
Other species not tested yet.
Data sheet 479_003.pdf
Cat. No.: 479 003
Amount: 50 µg
Price: $375.00
WB
Background

The inward rectifier potassium channels of the Kir2 subfamily consists of Kir2-1 – Kir2.4. They are widely and differentially expressed in the mammalian brain (1, 2), and exhibit the strongest difference between cellular potassium uptake and outward currents (1, 3). Kir2 potassium channels modulate cellular excitability, membrane potential, and the secretion of neurotransmitters and hormones (3).