Cat. No.: 479 003
Amount: 50 µg
Price:
$375.00
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| Cat. No. 479 003 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: not tested yet ICC: not tested yet IHC: not recommended |
| Immunogen | Recombinant protein corresponding to AA 398 to 445 from mouse Kir2.3 (UniProt Id: P52189) |
| Reactivity |
Reacts with: mouse (P52189), rat (P52190). Other species not tested yet. |
| Data sheet | 479_003.pdf |
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The inward rectifier potassium channels of the Kir2 subfamily consists of Kir2-1 – Kir2.4. They are widely and differentially expressed in the mammalian brain (1, 2), and exhibit the strongest difference between cellular potassium uptake and outward currents (1, 3). Kir2 potassium channels modulate cellular excitability, membrane potential, and the secretion of neurotransmitters and hormones (3).