Cat. No.: 377 011
Amount: 100 µg
Price:
$415.00
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| Cat. No. 377 011 |
100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Clone | 264D12 |
| Subtype | IgG2a (κ light chain) |
| Immunogen | Recombinant protein corresponding to AA 1 to 561 from rat Trim46 (UniProt Id: A0A0G2JXN2) |
| Epitop |
AA 1 to 114 from rat Trim46 (UniProt Id: A0A0G2JXN2) |
| Reactivity |
Reacts with: mouse (Q7TNM2), rat (A0A0G2JXN2). Other species not tested yet. |
| Specificity | K.O. validated |
| Data sheet | 377_011.pdf |
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The tripartite motif containing protein TRIM46, also referred to as TRIFIC, is a member of the C-I TRIM family, a subfamily of the RBCC (N-terminal RING finger/B-box/coiled coil)/TRIM superfamily.
TRIM46 localizes to newly specified axons and, at later stages, to the axon initial segment (AIS). By forming closely spaced parallel microtubule bundles it plays a crucial role in the initial polarization of neuronal cells.