Cat. No.: 369 004
Amount: 100 µl
Price:
$365.00
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| Cat. No. 369 004 |
100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: not tested yet ICC: not tested yet IHC: 1 : 500 gallery IHC-P: not recommended |
| Immunogen | Recombinant protein corresponding to AA 1 to 480 from mouse DDC (UniProt Id: O88533) |
| Reactivity |
Reacts with: mouse (O88533), rat (P14173). Other species not tested yet. |
| Specificity | DOPA decarboxylase |
| Data sheet | 369_004.pdf |
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DOPA decarboxylase, also referred to as aromatic L-amino acid decarboxylase, AADC or DDC, is the second enzyme in the biosynthesis of dopamine and serotonin. In addition, it is responsible for the synthesis of the trace amines phenylethylamine, p-tyramine, and tryptamine, which are considered to act as neuromodulators.
DDC is expressed in the central nervous system, but has also been detected in several tissues such as liver, kidney, small intestine, adrenal gland and blood vessels.
The inhibition of DDC is used for the treatment of Parkinson's disease.