Tailor-made Antibodies
and Tools for Life Science

CAML antibody - 359 004 K.O.

CAML is a receptor for TRC40/Asna1-mediated insertion of tail-anchored proteins
Guinea pig polyclonal antiserum
Cat. No.: 359 004
Amount: 100 µl
Price: $370.00
Cat. No. 359 004 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: not tested yet
IHC: not tested yet
IHC-P: not tested yet
Immunogen Recombinant protein corresponding to AA 1 to 187 from mouse CAML (UniProt Id: P49070)
Reactivity Reacts with: rat (Q6DGG9), mouse (P49070).
Other species not tested yet.
Specificity K.O. validated PubMed: 36055406
Data sheet 359_004.pdf

References for CAML - 359 004

The GET insertase exhibits conformational plasticity and induces membrane thinning.
McDowell MA, Heimes M, Enkavi G, Farkas Á, Saar D, Wild K, Schwappach B, Vattulainen I, Sinning I
Nature communications (2023) 141: 7355. 359 004 WB
ER entry pathway and glycosylation of GPI-anchored proteins are determined by N-terminal signal sequence and C-terminal GPI-attachment sequence.
Hirata T, Yang J, Tomida S, Tokoro Y, Kinoshita T, Fujita M, Kizuka Y
The Journal of biological chemistry (2022) : 102444. 359 004 WB; KO verified; tested species: human
A trap mutant reveals the physiological client spectrum of TRC40.
Coy-Vergara J, Rivera-Monroy J, Urlaub H, Lenz C, Schwappach B
Journal of cell science (2019) 13213: . 359 004 WB; tested species: human
Cat. No.: 359 004
Amount: 100 µl
Price: $370.00