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Cat. No. 347 104 |
100 µl antiserum, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
Applications | |
Immunogen | Synthetic peptide corresponding to residues near the amino terminus of mouse SOX1 (UniProt Id: P53783) |
Reactivity |
Reacts with: mouse (P53783), rat (A0A8I6G2U2). Other species not tested yet. Predicted to cross-react with human (O00570) due to high sequence homology. |
Data sheet | 347_104.pdf |
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Sex determining region of Y chromosome (Sry)-related high mobility group box1-3) or SOX1-3 proteins belong to the earliest transcription factors expressed in the developing CNS.
SOX1, SOX2 and SOX3 constitute the B1-subgroup of the SOX gene family 12. They are expressed by most progenitor cells of the developing CNS and are generally downregulated by neural cells when they exit the cell cycle and differentiate.