Cat. No.: 347 003
Amount: 50 µg
Price:
$375.00
Cat. No. 347 003 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
Applications |
Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section.', $event)" style="cursor: help;">IP: not tested yet Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section.', $event)" style="cursor: help;">ICC: 1 : 500 up to 1 : 1000 gallery Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section.', $event)" style="cursor: help;">IHC: 1 : 200 up to 1 : 500 gallery Immunohistochemistry (IHC-P) of formalin fixed, paraffin embedded (FFPE) tissue (some antibodies require special antigen retrieval steps, please refer to the ”Remarks” section). Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate.', $event)" style="cursor: help;">IHC-P: 1 : 200 gallery |
Immunogen | Synthetic peptide corresponding to residues near the carboxy terminus of mouse SOX2 (UniProt Id: P48432) |
Reactivity |
Reacts with: rat (D4A543), mouse (P48432), human (P48431). Other species not tested yet. |
Data sheet | 347_003.pdf |
Sex determining region of Y chromosome (Sry)-related high mobility group box1-3 or SOX 1-3 proteins belong to the earliest transcription factors expressed in the developing CNS
SOX1, SOX2 and SOX3 constitute the B1-subgroup of the Sox gene family 12. They are expressed by most progenitor cells of the developing CNS and are generally downregulated by neural cells when they exit the cell cycle and differentiate.