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Tbr1 antibody - 328 005

Tbr1 is a transcription factor involved in neuronal differentiation
Guinea pig polyclonal purified antibody
Cat. No.: 328 005
Amount: 50 µg
Price: $460.00
Cat. No. 328 005 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin was added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not recommended
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 1000 up to 1 : 2000 gallery  
IHC-P: 1 : 500 gallery  
Immunogen Synthetic peptide corresponding to AA 128 to 145 from rat Tbr1 (UniProt Id: D4A6N8)
Reactivity Reacts with: rat (D4A6N8), mouse (Q64336).
Other species not tested yet.
Data sheet 328_005.pdf

References for Tbr1 - 328 005

Generation of excitatory and inhibitory neurons from common progenitors via Notch signaling in the cerebellum.
Zhang T, Liu T, Mora N, Guegan J, Bertrand M, Contreras X, Hansen AH, Streicher C, Anderle M, Danda N, Tiberi L, et al.
Cell reports (2021) 3510: 109208. 328 005 IHC; tested species: mouse
53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination.
Callen E, Zong D, Wu W, Wong N, Stanlie A, Ishikawa M, Pavani R, Dumitrache LC, Byrum AK, Mendez-Dorantes C, Martinez P, et al.
Molecular cell (2020) 771: 26-38.e7. 328 005 IHC; tested species: mouse
DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.
Enriquez-Rios V, Dumitrache LC, Downing SM, Li Y, Brown EJ, Russell HR, McKinnon PJ
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 374: 893-905. 328 005 IHC; tested species: mouse
Cat. No.: 328 005
Amount: 50 µg
Price: $460.00
Generation of excitatory and inhibitory neurons from common progenitors via Notch signaling in the cerebellum.
Zhang T, Liu T, Mora N, Guegan J, Bertrand M, Contreras X, Hansen AH, Streicher C, Anderle M, Danda N, Tiberi L, et al.
Cell reports (2021) 3510: 109208. 328 005 IHC; tested species: mouse
53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination.
Callen E, Zong D, Wu W, Wong N, Stanlie A, Ishikawa M, Pavani R, Dumitrache LC, Byrum AK, Mendez-Dorantes C, Martinez P, et al.
Molecular cell (2020) 771: 26-38.e7. 328 005 IHC; tested species: mouse
DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.
Enriquez-Rios V, Dumitrache LC, Downing SM, Li Y, Brown EJ, Russell HR, McKinnon PJ
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 374: 893-905. 328 005 IHC; tested species: mouse
Background
Tbr 1 is a transcription factor of the T-box family that is highly expressed in glutamatergic early-born cortical projection neurons. It plays a role in the differentiation of intermediate progenitor cells (IPCs) into postmitotic projection neuron.