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NET antibody - 260 008

The NE transporter is involved in the termination of synaptic transmission
Rabbit monoclonal recombinant IgG
Cat. No.: 260 008
Amount: 50 µg
Price: $415.00
Cat. No. 260 008 50 µg purified recombinant IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not tested yet
IP: not tested yet
ICC: not tested yet
IHC: 1 : 500 gallery  
IHC-P: not tested yet
Clone Rb215A9
Subtype IgG1 (κ light chain)
Immunogen Synthetic peptide corresponding to residues surrounding AA 200 of rat NET. (UniProt Id: Q63380)
Reactivity Reacts with: rat (Q63380), mouse (O55192).
Other species not tested yet.
Remarks

This antibody is a chimeric antibody based on the monoclonal mouse antibody clone 215A9. The constant regions of the heavy and light chains have been replaced by rabbit specific sequences. Therefore, the antibody can be used with standard anti-rabbit secondary reagents. The antibody has been expressed in mammalian cells.

Data sheet 260_008.pdf
Cat. No.: 260 008
Amount: 50 µg
Price: $415.00
Background
The norepinephrine (NE) transporter (NET), also referred to as Sodium-dependent noradrenaline transporter, is expressed on the plasma membranes of noradrenergic neurons. It is responsible for the inactivation of synaptically released NE and is a target for many antidepressants and psychostimulants.