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Cre-recombinase antibody - 257 005

Cre-recombinase is used for conditional or tissue specific knockouts
Guinea pig polyclonal purified antibody
Cat. No.: 257 005
Amount: 50 µg
Price: $460.00
Cat. No. 257 005 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: not tested yet
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: 1 : 500 gallery  
IHC-P: 1 : 500 gallery  
Immunogen Full length recombinant Cre-recombinase from Bacteriophage P1. (UniProt Id: P06956)
Specificity Recognizes Cre- and iCre-recombinase.
Data sheet 257_005.pdf

References for Cre-recombinase - 257 005

Perivascular neurons instruct 3D vascular lattice formation via neurovascular contact.
Toma K, Zhao M, Zhang S, Wang F, Graham HK, Zou J, Modgil S, Shang WH, Tsai NY, Cai Z, Liu L, et al.
Cell (2024) 18711: 2767-2784.e23. 257 005 IHC; tested species: mouse
Cat. No.: 257 005
Amount: 50 µg
Price: $460.00
Perivascular neurons instruct 3D vascular lattice formation via neurovascular contact.
Toma K, Zhao M, Zhang S, Wang F, Graham HK, Zou J, Modgil S, Shang WH, Tsai NY, Cai Z, Liu L, et al.
Cell (2024) 18711: 2767-2784.e23. 257 005 IHC; tested species: mouse
Background
Cre-Recombinase is a 38 kDa type 1 topoisomerase from bacteriophage P1. It is highly specific for a 34 bp DNA sequence (loxP) found in P1 DNA and catalyzes site-specific recombination between two 34-base-pair LOXP recognition sites. Its role is to maintain the phage genome as a monomeric unit-copy plasmid in the lysogenic state. Its highly specific catalytic activity makes it a valuable tool for the generation of conditional or tissue specific mutants.