Cat. No.: 216 008
Amount: 50 µg
Price:
$420.00
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| Cat. No. 216 008 |
50 µg purified recombinant IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Clone | Rb62-2E8 |
| Subtype | IgG1 (κ light chain) |
| Immunogen | Recombinant protein corresponding to residues near the C-terminus of rat ChT (UniProt Id: Q9JMD7) |
| Reactivity |
Reacts with: mouse (Q8BGY9), rat (Q9JMD7), monkey. Other species not tested yet. |
| Remarks |
This antibody is a chimeric antibody based on the monoclonal mouse antibody 62-2E8. The constant regions of the heavy and light chains have been replaced with rabbit specific sequences. This antibody can therefore be used with standard anti-rabbit secondary reagents. The antibody has been expressed in mammalian cells. |
| Data sheet | 216_008.pdf |
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Acetylcholine (ACh) functions as a neurotransmitter in both the central and peripheral nervous systems of all vertebrates, and is the principal neurotransmitter used at the neuromuscular junction. This neurotransmitter is synthesized from choline (Ch) and acetyl-coenzyme A by choline acetyltransferase (ChAT). For this pathway choline is required, which neurons acquire through high-affinity choline transporters (ChTs). ChT have been found on the presynaptic membrane but also on ACh containing synaptic vesicles.