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Home > Products > 213 104

Tyrosine hydroxylase antibody - 213 104

Tyrosine hydroxylase is the rate limiting enzyme in catecholamine synthesis
Guinea pig polyclonal antiserum
Cat. No.: 213 104
Amount: 100 µl
Price: $370.00
Cat. No. 213 104 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: not tested yet
IHC: 1 : 500 gallery  
IHC-P: 1 : 500 gallery  
Immunogen Recombinant protein corresponding to residues near the amino-terminus of rat TyrH. (UniProt Id: P04177)
Reactivity Reacts with: rat (P04177), mouse (P24529).
Other species not tested yet.
Data sheet 213_104.pdf

References for Tyrosine hydroxylase - 213 104

The proteomic landscape of synaptic diversity across brain regions and cell types.
van Oostrum M, Blok TM, Giandomenico SL, Tom Dieck S, Tushev G, Fürst N, Langer JD, Schuman EM
Cell (2023) 18624: 5411-5427.e23. 213 104 IHC, WB; tested species: mouse
Functional hyperactivity in long QT syndrome type 1 pluripotent stem cell-derived sympathetic neurons.
Winbo A, Ramanan S, Eugster E, Rydberg A, Jovinge S, Skinner JR, Montgomery JM
American journal of physiology. Heart and circulatory physiology (2021) 3211: H217-H227. 213 104 ICC; tested species: human
Synaptotagmin-1 is the Ca2+ sensor for fast striatal dopamine release.
Banerjee A, Lee J, Nemcova P, Liu C, Kaeser PS
eLife (2020) 9: . 213 104 ICC, IHC; tested species: mouse
Functional Coculture of Sympathetic Neurons and Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells.
Winbo A, Ramanan S, Eugster E, Jovinge S, Skinner JR, Montgomery JM
American journal of physiology. Heart and circulatory physiology (2020) : . 213 104 ICC; tested species: human
Dopamine Secretion Is Mediated by Sparse Active Zone-like Release Sites.
Liu C, Kershberg L, Wang J, Schneeberger S, Kaeser PS
Cell (2018) 1724: 706-718.e15. 213 104 ICC, IHC; tested species: mouse
Coordinating brain-distributed network activities in memory resistant to extinction.
Clarke-Williams CJ, Lopes-Dos-Santos V, Lefèvre L, Brizee D, Causse AA, Rothaermel R, Hartwich K, Perestenko PV, Toth R, McNamara CG, Sharott A, et al.
Cell (2024) 1872: 409-427.e19. 213 104 IHC; tested species: mouse
Deficiency of Perry syndrome-associated p150Glued in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum abnormalities.
Yu J, Yang X, Zheng J, Sgobio C, Sun L, Cai H
NPJ Parkinson's disease (2023) 91: 35. 213 104 IHC; tested species: mouse
The proteomic landscape of synaptic diversity across brain regions and cell types.
van Oostrum M, Blok TM, Giandomenico SL, Tom Dieck S, Tushev G, Fürst N, Langer JD, Schuman EM
Cell (2023) 18624: 5411-5427.e23. 213 104 IHC, WB; tested species: mouse
Neuronal Adenosine A1 Receptor is Critical for Olfactory Function but Unable to Attenuate Olfactory Dysfunction in Neuroinflammation.
Schubert C, Schulz K, Träger S, Plath AL, Omriouate A, Rosenkranz SC, Morellini F, Friese MA, Hirnet D
Frontiers in cellular neuroscience (2022) 16: 912030. 213 104 IHC; tested species: mouse
A glutaminyl cyclase-catalyzed α-synuclein modification identified in human synucleinopathies.
Hartlage-Rübsamen M, Bluhm A, Moceri S, Machner L, Köppen J, Schenk M, Hilbrich I, Holzer M, Weidenfeller M, Richter F, Coras R, et al.
Acta neuropathologica (2021) : . 213 104 IHC; tested species: mouse
Presence of ethanol-sensitive and ethanol-insensitive glycine receptors in the ventral tegmental area and prefrontal cortex in mice.
Araya A, Gallegos S, Viveros R, San Martin L, Muñoz B, Harvey RJ, Zeilhofer HU, Aguayo LG
British journal of pharmacology (2021) 17823: 4691-4707. 213 104 IHC; tested species: mouse
Evidence of structural and functional plasticity occurring within the intracardiac nervous system of spontaneously hypertensive rats.
Ashton JL, Argent LP, Smith JE, Jin S, Sands GB, Smaill BH, Montgomery JM
American journal of physiology. Heart and circulatory physiology (2020) : . 213 104 IHC; tested species: rat
Synaptotagmin-1 is the Ca2+ sensor for fast striatal dopamine release.
Banerjee A, Lee J, Nemcova P, Liu C, Kaeser PS
eLife (2020) 9: . 213 104 ICC, IHC; tested species: mouse
THC Regulates Tearing via Cannabinoid CB1 Receptors.
Thayer A, Murataeva N, Delcroix V, Wager-Miller J, Makarenkova HP, Straiker A
Investigative ophthalmology & visual science (2020) 6110: 48. 213 104 IHC; tested species: mouse
In vivo functional diversity of midbrain dopamine neurons within identified axonal projections.
Farassat N, Costa KM, Stojanovic S, Albert S, Kovacheva L, Shin J, Egger R, Somayaji M, Duvarci S, Schneider G, Roeper J, et al.
eLife (2019) 8: . 213 104 IHC; tested species: mouse
Dopamine Secretion Is Mediated by Sparse Active Zone-like Release Sites.
Liu C, Kershberg L, Wang J, Schneeberger S, Kaeser PS
Cell (2018) 1724: 706-718.e15. 213 104 ICC, IHC; tested species: mouse
Characterization of the axon initial segment of mice substantia nigra dopaminergic neurons.
González-Cabrera C, Meza R, Ulloa L, Merino-Sepúlveda P, Luco V, Sanhueza A, Oñate-Ponce A, Bolam JP, Henny P
The Journal of comparative neurology (2017) 52516: 3529-3542. 213 104 IHC; tested species: mouse
Spike-Dependent Dynamic Partitioning of the Locus Coeruleus Network through Noradrenergic Volume Release in a Simulation of the Nucleus Core.
Baral S, Hosseini H, More K, Fabrin TMC, Braun J, Prigge M
Brain sciences (2022) 126: . 213 104 ExM; tested species: mouse
Multiplex imaging of human induced pluripotent stem cell-derived neurons with CO-Detection by indEXing (CODEX) technology.
Heinrich L, Zafar F, Morato Torres CA, Singh J, Khan A, Chen MY, Hempel C, Nikulina N, Mulholland J, Braubach O, Schüle B, et al.
Journal of neuroscience methods (2022) : 109653. 213 104 Codex-PC; tested species: human
Cat. No.: 213 104
Amount: 100 µl
Price: $370.00
The proteomic landscape of synaptic diversity across brain regions and cell types.
van Oostrum M, Blok TM, Giandomenico SL, Tom Dieck S, Tushev G, Fürst N, Langer JD, Schuman EM
Cell (2023) 18624: 5411-5427.e23. 213 104 IHC, WB; tested species: mouse
Functional hyperactivity in long QT syndrome type 1 pluripotent stem cell-derived sympathetic neurons.
Winbo A, Ramanan S, Eugster E, Rydberg A, Jovinge S, Skinner JR, Montgomery JM
American journal of physiology. Heart and circulatory physiology (2021) 3211: H217-H227. 213 104 ICC; tested species: human
Synaptotagmin-1 is the Ca2+ sensor for fast striatal dopamine release.
Banerjee A, Lee J, Nemcova P, Liu C, Kaeser PS
eLife (2020) 9: . 213 104 ICC, IHC; tested species: mouse
Functional Coculture of Sympathetic Neurons and Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells.
Winbo A, Ramanan S, Eugster E, Jovinge S, Skinner JR, Montgomery JM
American journal of physiology. Heart and circulatory physiology (2020) : . 213 104 ICC; tested species: human
Dopamine Secretion Is Mediated by Sparse Active Zone-like Release Sites.
Liu C, Kershberg L, Wang J, Schneeberger S, Kaeser PS
Cell (2018) 1724: 706-718.e15. 213 104 ICC, IHC; tested species: mouse
Coordinating brain-distributed network activities in memory resistant to extinction.
Clarke-Williams CJ, Lopes-Dos-Santos V, Lefèvre L, Brizee D, Causse AA, Rothaermel R, Hartwich K, Perestenko PV, Toth R, McNamara CG, Sharott A, et al.
Cell (2024) 1872: 409-427.e19. 213 104 IHC; tested species: mouse
Deficiency of Perry syndrome-associated p150Glued in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum abnormalities.
Yu J, Yang X, Zheng J, Sgobio C, Sun L, Cai H
NPJ Parkinson's disease (2023) 91: 35. 213 104 IHC; tested species: mouse
The proteomic landscape of synaptic diversity across brain regions and cell types.
van Oostrum M, Blok TM, Giandomenico SL, Tom Dieck S, Tushev G, Fürst N, Langer JD, Schuman EM
Cell (2023) 18624: 5411-5427.e23. 213 104 IHC, WB; tested species: mouse
Neuronal Adenosine A1 Receptor is Critical for Olfactory Function but Unable to Attenuate Olfactory Dysfunction in Neuroinflammation.
Schubert C, Schulz K, Träger S, Plath AL, Omriouate A, Rosenkranz SC, Morellini F, Friese MA, Hirnet D
Frontiers in cellular neuroscience (2022) 16: 912030. 213 104 IHC; tested species: mouse
A glutaminyl cyclase-catalyzed α-synuclein modification identified in human synucleinopathies.
Hartlage-Rübsamen M, Bluhm A, Moceri S, Machner L, Köppen J, Schenk M, Hilbrich I, Holzer M, Weidenfeller M, Richter F, Coras R, et al.
Acta neuropathologica (2021) : . 213 104 IHC; tested species: mouse
Presence of ethanol-sensitive and ethanol-insensitive glycine receptors in the ventral tegmental area and prefrontal cortex in mice.
Araya A, Gallegos S, Viveros R, San Martin L, Muñoz B, Harvey RJ, Zeilhofer HU, Aguayo LG
British journal of pharmacology (2021) 17823: 4691-4707. 213 104 IHC; tested species: mouse
Evidence of structural and functional plasticity occurring within the intracardiac nervous system of spontaneously hypertensive rats.
Ashton JL, Argent LP, Smith JE, Jin S, Sands GB, Smaill BH, Montgomery JM
American journal of physiology. Heart and circulatory physiology (2020) : . 213 104 IHC; tested species: rat
Synaptotagmin-1 is the Ca2+ sensor for fast striatal dopamine release.
Banerjee A, Lee J, Nemcova P, Liu C, Kaeser PS
eLife (2020) 9: . 213 104 ICC, IHC; tested species: mouse
THC Regulates Tearing via Cannabinoid CB1 Receptors.
Thayer A, Murataeva N, Delcroix V, Wager-Miller J, Makarenkova HP, Straiker A
Investigative ophthalmology & visual science (2020) 6110: 48. 213 104 IHC; tested species: mouse
In vivo functional diversity of midbrain dopamine neurons within identified axonal projections.
Farassat N, Costa KM, Stojanovic S, Albert S, Kovacheva L, Shin J, Egger R, Somayaji M, Duvarci S, Schneider G, Roeper J, et al.
eLife (2019) 8: . 213 104 IHC; tested species: mouse
Dopamine Secretion Is Mediated by Sparse Active Zone-like Release Sites.
Liu C, Kershberg L, Wang J, Schneeberger S, Kaeser PS
Cell (2018) 1724: 706-718.e15. 213 104 ICC, IHC; tested species: mouse
Characterization of the axon initial segment of mice substantia nigra dopaminergic neurons.
González-Cabrera C, Meza R, Ulloa L, Merino-Sepúlveda P, Luco V, Sanhueza A, Oñate-Ponce A, Bolam JP, Henny P
The Journal of comparative neurology (2017) 52516: 3529-3542. 213 104 IHC; tested species: mouse
Spike-Dependent Dynamic Partitioning of the Locus Coeruleus Network through Noradrenergic Volume Release in a Simulation of the Nucleus Core.
Baral S, Hosseini H, More K, Fabrin TMC, Braun J, Prigge M
Brain sciences (2022) 126: . 213 104 ExM; tested species: mouse
Multiplex imaging of human induced pluripotent stem cell-derived neurons with CO-Detection by indEXing (CODEX) technology.
Heinrich L, Zafar F, Morato Torres CA, Singh J, Khan A, Chen MY, Hempel C, Nikulina N, Mulholland J, Braubach O, Schüle B, et al.
Journal of neuroscience methods (2022) : 109653. 213 104 Codex-PC; tested species: human
WB
IHC
IHC
IHC-P
Background
Tyrosine hydroxylase is one of the key enzymes in the synthesis pathway of catecholamines like adrenalin, noradrenalin and dopamin and is frequently used as a marker for dopaminergic neurons. This neuronal subpopulation is especially affected in Parkinson's disease.
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