Synaptic Systems - Parvalbumin

Cat. No.: 195 006

Amount: 200 µl

Price: $370.00

For the import of chicken antibodies into the USA you need a special import permit. This can be applied for at your USDA office. If you cannot apply for this, please order the chicken antibodies through our distributor Cedarlane USA. If you have any questions, please contact us.

Cat. No. 195 006	200 µl antibody, lyophilized. For reconstitution add 200 µl H₂O, then aliquot and store at -20°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications	WB: not tested yet (see remarks) IP: yes ICC: not tested yet IHC: 1 : 500 gallery IHC-P: 1 : 200 gallery
Immunogen	Full-length recombinant rat Parvalbumin (UniProt Id: P02625)
Reactivity	Reacts with: rat (P02625), mouse (P32848). Other species not tested yet.
Matching control protein/peptide	195-0P
Remarks	WB: The rabbit polyclonal antiserum (cat. no. 195 002) is recommended for westernblotting. Due to its small size, a tricine gel should be used.
Data sheet	195_006.pdf

References for Parvalbumin - 195 006

WB (1)
ICC (2)
IHC (13)

Brevican, Neurocan, Tenascin-C, and Tenascin-R Act as Important Regulators of the Interplay Between Perineuronal Nets, Synaptic Integrity, Inhibitory Interneurons, and Otx2.
Mueller-Buehl C, Reinhard J, Roll L, Bader V, Winklhofer KF, Faissner A
Frontiers in cell and developmental biology (2022) 10: 886527. 195 006 WB, IHC; tested species: mouse

Focal clusters of peri-synaptic matrix contribute to activity-dependent plasticity and memory in mice.
Chelini G, Mirzapourdelavar H, Durning P, Baidoe-Ansah D, Sethi MK, O'Donovan SM, Klengel T, Balasco L, Berciu C, Boyer-Boiteau A, McCullumsmith R, et al.
Cell reports (2024) 435: 114112. 195 006 ICC; tested species: mouse

The antipsychotic drugs olanzapine and haloperidol modify network connectivity and spontaneous activity of neural networks in vitro.
Dzyubenko E, Juckel G, Faissner A
Scientific reports (2017) 71: 11609. 195 006 ICC; tested species: mouse

Creation of a novel CRISPR-generated allele to express HA epitope-tagged C1QL1 and improved methods for its detection at synapses.
Cheung HW, Schouw AD, Altunay ZM, Maddox JW, Kresic LC, McAllister BC, Caro K, Alam S, Huang A, Pijewski RS, Lee A, et al.
FEBS letters (2024) : . 195 006 IHC; tested species: mouse

Calretinin-Expressing Synapses Show Improved Synaptic Efficacy with Reduced Asynchronous Release during High-Rate Activity.
Zhang C, Wang M, Lin S, Xie R
The Journal of neuroscience : the official journal of the Society for Neuroscience (2022) 4213: 2729-2742. 195 006 IHC; tested species: mouse

C1ql1 is expressed in adult outer hair cells of the cochlea in a tonotopic gradient.
Biswas J, Pijewski RS, Makol R, Miramontes TG, Thompson BL, Kresic LC, Burghard AL, Oliver DL, Martinelli DC
PloS one (2021) 165: e0251412. 195 006 IHC; tested species: mouse

Anoctamin 2-chloride channels reduce simple spike activity and mediate inhibition at elevated calcium concentration in cerebellar Purkinje cells.
Auer F, Franco Taveras E, Klein U, Kesenheimer C, Fleischhauer D, Möhrlen F, Frings S
PloS one (2021) 163: e0247801. 195 006 IHC; tested species: mouse

Autoantibodies against NMDA receptor 1 modify rather than cause encephalitis.
Wilke JBH, Hindermann M, Berghoff SA, Zihsler S, Arinrad S, Ronnenberg A, Barnkothe N, Steixner-Kumar AA, Röglin S, Stöcker W, Hollmann M, et al.
Molecular psychiatry (2021) : . 195 006 IHC; tested species: mouse

Microglia Depletion-Induced Remodeling of Extracellular Matrix and Excitatory Synapses in the Hippocampus of Adult Mice.
Strackeljan L, Baczynska E, Cangalaya C, Baidoe-Ansah D, Wlodarczyk J, Kaushik R, Dityatev A
Cells (2021) 108: . 195 006 IHC; tested species: mouse

Spatial Expression Pattern of the Major Ca2+-Buffer Proteins in Mouse Retinal Ganglion Cells.
Kovács-Öller T, Szarka G, Tengölics ÁJ, Ganczer A, Balogh B, Szabó-Meleg E, Nyitrai M, Völgyi B
Cells (2020) 94: . 195 006 IHC; tested species: mouse

Subcellular sorting of neuregulins controls the assembly of excitatory-inhibitory cortical circuits.
Exposito-Alonso D, Osório C, Bernard C, Pascual-García S, Del Pino I, Marín O, Rico B
eLife (2020) 9: . 195 006 IHC; tested species: mouse

Npas1+-Nkx2.1+ Neurons Are an Integral Part of the Cortico-pallido-cortical Loop.
Abecassis ZA, Berceau BL, Win PH, García D, Xenias HS, Cui Q, Pamukcu A, Cherian S, Hernández VM, Chon U, Lim BK, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2020) 404: 743-768. 195 006 IHC; tested species: mouse

Selective Inactivation of Reelin in Inhibitory Interneurons Leads to Subtle Changes in the Dentate Gyrus But Leaves Cortical Layering and Behavior Unaffected.
Pahle J, Muhia M, Wagener RJ, Tippmann A, Bock HH, Graw J, Herz J, Staiger JF, Drakew A, Kneussel M, Rune GM, et al.
Cerebral cortex (New York, N.Y. : 1991) (2019) : . 195 006 IHC; tested species: mouse

Increased Excitability and Reduced Excitatory Synaptic Input Into Fast-Spiking CA2 Interneurons After Enzymatic Attenuation of Extracellular Matrix.
Hayani H, Song I, Dityatev A
Frontiers in cellular neuroscience (2018) 12: 149. 195 006 IHC; tested species: mouse

Activity-Dependent Gating of Parvalbumin Interneuron Function by the Perineuronal Net Protein Brevican.
Favuzzi E, Marques-Smith A, Deogracias R, Winterflood CM, Sánchez-Aguilera A, Mantoan L, Maeso P, Fernandes C, Ewers H, Rico B
Neuron (2017) 953: 639-655.e10. 195 006 IHC; tested species: mouse

Cat. No.: 195 006

Amount: 200 µl

Price: $370.00

References
WB (1)
ICC (2)
IHC (13)

IHC

IHC-P

Background

Parvalbumin is a small, acidic calcium binding protein and belongs to the family of EF hand proteins. The protein is found in skeletal muscle and the brain of vertebrates where it locates to a specific population of GABAergic interneurons. This subset of neurons may contribute to maintaining the balance between excitation and inhibition in the cortex and the hippocampus.

1 ) Andrioli A et al., Neuroscience (2007)
2 ) Hendrickson A et al., Exp. Eye Res. (2007)
3 ) Fukuda T et al., Neuroscience (2003)
4 ) Kosaka K et al., Exp Brain Res (1994)
5 ) Tolosa de Talamoni N et al., Proc. Natl. Acad. Sci. U.S.A. (1993)
6 ) Kubota Y et al., Neuroreport (1993)

Protocols

Standard protocol

IHC

Free floating
Slide mounted
Tissue preparation
Pre-adsorption protocol

IHC-P

Chromogenic detection
Fluorescent detection
Tissue preparation
Pre-adsorption protocol

OTHER

Preabsorbtion

Other products for this target

Parvalbumin antibody - 195 006

References for Parvalbumin - 195 006