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Home > Products > 180 203

GluK3 antibody - 180 203

GluKs are ligand-gated ion channel involved in excitatory neurotransmission
Rabbit polyclonal purified antibody
Cat. No.: 180 203
Amount: 50 µg
Price: $375.00
Cat. No. 180 203 50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: not tested yet
IHC: yes
IHC-P: not tested yet
Immunogen Recombinant protein corresponding to AA 845 to 919 from rat GluK3 (UniProt Id: P42264)
Reactivity Reacts with: human (Q13003), rat (P42264), mouse (B1AS29).
Other species not tested yet.
Data sheet 180_203.pdf

References for GluK3 - 180 203

Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus.
Marrocco J, Mairesse J, Ngomba RT, Silletti V, Van Camp G, Bouwalerh H, Summa M, Pittaluga A, Nicoletti F, Maccari S, Morley-Fletcher S, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2012) 3248: 17143-54. 180 203 WB
Localization of kainate receptors in inner and outer hair cell synapses.
Fujikawa T, Petralia RS, Fitzgerald TS, Wang YX, Millis B, Morgado-Díaz JA, Kitamura K, Kachar B
Hearing research (2014) 314: 20-32. 180 203 IHC; tested species: rat
Cat. No.: 180 203
Amount: 50 µg
Price: $375.00
Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus.
Marrocco J, Mairesse J, Ngomba RT, Silletti V, Van Camp G, Bouwalerh H, Summa M, Pittaluga A, Nicoletti F, Maccari S, Morley-Fletcher S, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2012) 3248: 17143-54. 180 203 WB
Localization of kainate receptors in inner and outer hair cell synapses.
Fujikawa T, Petralia RS, Fitzgerald TS, Wang YX, Millis B, Morgado-Díaz JA, Kitamura K, Kachar B
Hearing research (2014) 314: 20-32. 180 203 IHC; tested species: rat
WB
Background

Ionotropic glutamate receptors (iGluRs) mediate rapid excitatory neurotransmission in the mammalian CNS. They can be subdivided into three major groups, the AMPA/GluA, NMDA/GluN, and kainate/GluK receptors (KARs) (1, 2).
mRNAs coding for glutamate receptors are substrates for an adenosine deaminase acting on RNA (ADAR) that increases the diversity of these proteins (3). KARs can be found at pre- and postsynaptic sites and are composed of five different subunits: GluK1, GluK2 and GluK3 can form homomeric receptors whereas GluK4 and GluK5 form heteromeric receptors with GluK1-3 (4).