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Neurofilament L antibody - 171 014

Neurofilaments are major neuronal intermediate filaments
Guinea pig polyclonal antiserum
Cat. No.: 171 014
Amount: 100 µl
Price: $365.00
Cat. No. 171 014 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 500 up to 1 : 1000 gallery  
IHCgallery  
IHC-P: 1 : 250 gallery  
Immunogen Recombinant protein corresponding to residues near the carboxy terminus of rat Neurofilament L. (UniProt Id: P19527)
Reactivity Reacts with: mouse (P08551), rat (P19527).
Other species not tested yet.
Data sheet 171_014.pdf

References for Neurofilament L - 171 014

Neuraminidase inhibition promotes the collective migration of neurons and recovery of brain function.
Matsumoto M, Matsushita K, Hane M, Wen C, Kurematsu C, Ota H, Bang Nguyen H, Quynh Thai T, Herranz-Pérez V, Sawada M, Fujimoto K, et al.
EMBO molecular medicine (2024) : . 171 014 IHC; tested species: mouse
Cat. No.: 171 014
Amount: 100 µl
Price: $365.00
Neuraminidase inhibition promotes the collective migration of neurons and recovery of brain function.
Matsumoto M, Matsushita K, Hane M, Wen C, Kurematsu C, Ota H, Bang Nguyen H, Quynh Thai T, Herranz-Pérez V, Sawada M, Fujimoto K, et al.
EMBO molecular medicine (2024) : . 171 014 IHC; tested species: mouse
Background
Neurofilaments are exclusively expressed in nerve cells and are the major structural component of large-diameter myelinated axons. They are predominatly composed of three proteins, Neurofilament H, L and M and are among the most highly phosphorylated neuronal proteins.