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Neurofilament L antibody - 171 008

Neurofilaments are major neuronal intermediate filaments
Rabbit monoclonal recombinant IgG
Cat. No.: 171 008
Amount: 50 µg
Price: $415.00
Cat. No. 171 008 50 µg purified recombinant IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 up to 1 : 5000 gallery  
IP: not tested yet
ICC: 1 : 500 up to 1 : 1000 gallery  
IHC: 1 : 1000 gallery  
IHC-P: 1 : 5000 gallery  
Clone Rb69H10
Subtype IgG1 (κ light chain)
Immunogen Recombinant protein corresponding to residues near the carboxy terminus of rat Neurofilament L. (UniProt Id: P19527)
Reactivity Reacts with: mouse (P08551), rat (P19527).
Other species not tested yet.
Remarks

This antibody is a chimeric antibody based on the monoclonal mouse antibody clone 69H10. The constant regions of the heavy and light chains have been replaced by rabbit specific sequences. Therefore, the antibody can be used with standard anti-rabbit secondary reagents. The antibody has been expressed in mammalian cells.

Data sheet 171_008.pdf
Cat. No.: 171 008
Amount: 50 µg
Price: $415.00
Background
Neurofilaments are exclusively expressed in nerve cells and are the major structural component of large-diameter myelinated axons. They are predominatly composed of three proteins, Neurofilament H, L and M and are among the most highly phosphorylated neuronal proteins.