Cat. No.: 162 111
Amount: 100 µg
Price:
$415.00
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| Cat. No. 162 111 |
100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Clone | 151E3 |
| Subtype | IgG2a (κ light chain) |
| Immunogen | Recombinant protein corresponding to residues near the carboxy terminus of rat Shank3 (UniProt Id: Q9JLU4) |
| Reactivity |
Reacts with: rat (Q9JLU4, Q9WV48, Q9QX74), mouse (Q4ACU6, D3Y2U1, Q80238). Other species not tested yet. |
| Specificity | Recognizes Shank 1, 2 and 3. |
| Remarks |
IHC: Fix for 15 min with 4% PFA and 15% picric acid in PBS. |
| Data sheet | 162_111.pdf |
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Shank1, 2 and 3 are major proteins of the postsynaptic density (PSD). They are composed of several protein-protein interaction domains like PDZ-, homer- and ABP1-binding domains which allow them to crosslink ionotopic and metabotropic glutamate receptor complexes with each other and to the actin-cytoskeleton.