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Homer1b/c antibody - 160 111AbRED

Homer1, 2 and 3 are post synaptic density (PSD) proteins involved in the targeting of glutamate receptors
Mouse monoclonal purified IgG
Cat. No.: 160 111AbRED
Amount: 100 µg
Price: $465.00
Cat. No. 160 111AbRED 100 µg purified IgG, lyophilized, fluorescence-labeled with abberior STAR RED.

abberior STAR® dyes have been especially developed for for Stimulated Emission Depletion (STED) microscopy which allows higher resolution imaging compared to confocal laser scanning microscopy. For many of the fluorescence labeled antibodies conjugated to abberior STAR® dyes established fluorescence detection systems can be used.

abberior STAR® 635P: λex 638 nm / λem 651 nm
abberior STAR® ORANGE: λex 589 nm / λem 616 nm
abberior STAR® RED: λex 638 nm / λem 655 nm
 

This product or portions thereof is manufactured under license from abberior GmbH.
abberior STAR is a trademark of abberior GmbH, Goettingen/Germany.
Purchase of reagents related to the abberior STAR technology from Synaptic Systems GmbH provides a license for non-profit and in-house research use only. Any application of above mentioned technology for commercial purpose requires a separate license from abberior GmbH.

Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Either add 1:1 (v/v) glycerol, then aliquot and store at -20°C until use, or store aliquots at -80°C without additives.
Reconstitute immediately upon receipt! Avoid bright light when working with the antibody to minimize photo bleeching of the fluorescent dye.
Applications
 
WB: N/A
IP: N/A
ICC: 1 : 300 (see remarks) gallery  
IHC: not tested yet
IHC-P: not tested yet
Label abberior STAR RED
Clone SY-72G2
Subtype IgG1 (κ light chain)
Immunogen Recombinant protein corresponding to the c-terminal half of human Homer1b (UniProt Id: Q86YM7-1)
Reactivity Reacts with: mouse (Q9Z2Y3), rat (Q9Z214), human (Q86YM7-1).
Other species not tested yet.
Specificity Specific for Homer1b and 1c; no cross-reactivity to Homer1a
Remarks

ICC: This antibody conjugate is especially suitable for high resolution STED microscopy.

Data sheet 160_111abred.pdf
Cat. No.: 160 111AbRED
Amount: 100 µg
Price: $465.00
Background

Homer is a scaffolding protein of the post synaptic density (PSD) and enriched at excitatory synapses. The protein binds metabotropic glutamate receptors, TRPC1, proteins of the Shank family and others. By aggregating these proteins into clusters, homer was suggested to organize distinct signalling domains.
Three isoforms, Homer1, 2 and 3 have been described. Each of these isoforms is subject to alternative splicing yielding the splice variants a, b, c, d.