Cat. No.: 152 311
Amount: 100 µg
Price:
$420.00
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| Cat. No. 152 311 |
100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: not tested yet ICC: not tested yet IHC: not tested yet IHC-P: not tested yet |
| Clone | 163E3 |
| Subtype | IgG2b (κ light chain) |
| Immunogen | Recombinant protein corresponding to AA 2056 to 2336 from rat Ca2+ channel N-type α-1B (Cav2.2) (UniProt Id: Q02294) |
| Epitop |
AA 2074 to 2354 from rat Ca2+ channel N-type α-1B (Cav2.2) (UniProt Id: Q02294) |
| Reactivity |
Reacts with: rat (Q02294), mouse. Other species not tested yet. |
| Matching control protein/peptide | 152-3P |
| Remarks |
WB: To avoid protein aggregation, do not heat samples for SDS-PAGE. |
| Data sheet | 152_311.pdf |
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Voltage gated calcium channels (VGCCs), also referred to as voltage sensitive calcium channels (VSCCs), are present in most excitable cells. They mediate the influx of Ca2+ ions into the cell and trigger the release of neurotransmitters or hormons but are also involved in other calcium dependent processes like metabolism, cell proliferation and cell death.
VGCCs are composed of four subunits (α-1, α-2, β and δ) in a 1:1:1:1 ratio. The α-1A isoform occurs in VGCCs of the P/Q-type while isoform α-1B is found in the N-type. Both belong to the high voltage activated group (hva).