Neuroinflammation induces synaptic scaling through IL-1β-mediated activation of the transcriptional repressor REST/NRSF.Buffolo F, Petrosino V, Albini M, Moschetta M, Carlini F, Floss T, Kerlero de Rosbo N, Cesca F, Rocchi A, Uccelli A, Benfenati F, et al.
Cell death & disease (2021) 122: 180.
147 011 ICC; tested species: mouse
Local miRNA-Dependent Translational Control of GABAAR Synthesis during Inhibitory Long-Term Potentiation.Rajgor D, Purkey AM, Sanderson JL, Welle TM, Garcia JD, Dell'Acqua ML, Smith KR
Cell reports (2020) 3112: 107785.
147 011 ICC; tested species: rat
Imbalance of Excitatory/Inhibitory Neuron Differentiation in Neurodevelopmental Disorders with an NR2F1 Point Mutation.Zhang K, Yu F, Zhu J, Han S, Chen J, Wu X, Chen Y, Shen T, Liao J, Guo W, Yang X, et al.
Cell reports (2020) 313: 107521.
147 011 ICC; tested species: human
Acute knockdown of Depdc5 leads to synaptic defects in mTOR-related epileptogenesis.De Fusco A, Cerullo MS, Marte A, Michetti C, Romei A, Castroflorio E, Baulac S, Benfenati F
Neurobiology of disease (2020) : 104822.
147 011 ICC; tested species: mouse
Opposite Control of Excitatory and Inhibitory Synapse Formation by Slitrk2 and Slitrk5 on Dopamine Neurons Modulates Hyperactivity Behavior.Salesse C, Charest J, Doucet-Beaupré H, Castonguay AM, Labrecque S, De Koninck P, Lévesque M
Cell reports (2020) 307: 2374-2386.e5.
147 011 ICC; tested species: mouse
Chemico-genetic discovery of astrocytic control of inhibition in vivo.Takano T, Wallace JT, Baldwin KT, Purkey AM, Uezu A, Courtland JL, Soderblom EJ, Shimogori T, Maness PF, Eroglu C, Soderling SH, et al.
Nature (2020) : .
147 011 WB, ICC; tested species: mouse
Activated microglia cause metabolic disruptions in developmental cortical interneurons that persist in interneurons from individuals with schizophrenia.Park GH, Noh H, Shao Z, Ni P, Qin Y, Liu D, Beaudreault CP, Park JS, Abani CP, Park JM, Le DT, et al.
Nature neuroscience (2020) 2311: 1352-1364.
147 011 ICC; tested species: human
A GTPase-induced switch in phospholipid affinity of collybistin contributes to synaptic gephyrin clustering.Kilisch M, Mayer S, Mitkovski M, Roehse H, Hentrich J, Schwappach B, Papadopoulos T
Journal of cell science (2020) : .
147 011 ICC; tested species: rat
Nanoscale Subsynaptic Domains Underlie the Organization of the Inhibitory Synapse.Crosby KC, Gookin SE, Garcia JD, Hahm KM, Dell'Acqua ML, Smith KR
Cell reports (2019) 2612: 3284-3297.e3.
147 011 ICC, IHC; tested species: rat
Autism and Schizophrenia-Associated CYFIP1 Regulates the Balance of Synaptic Excitation and Inhibition.Davenport EC, Szulc BR, Drew J, Taylor J, Morgan T, Higgs NF, López-Doménech G, Kittler JT
Cell reports (2019) 268: 2037-2051.e6.
147 011 WB, ICC, IHC; tested species: mouse
Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins.Kasaragod VB, Hausrat TJ, Schaefer N, Kuhn M, Christensen NR, Tessmer I, Maric HM, Madsen KL, Sotriffer C, Villmann C, Kneussel M, et al.
Neuron (2019) 1014: 673-689.e11.
147 011 ICC; tested species: mouse
βPix heterozygous mice have defects in neuronal morphology and social interaction.Kwon Y, Lee SJ, Lee E, Kim D, Park D
Biochemical and biophysical research communications (2019) 5164: 1204-1210.
147 011 ICC; tested species: mouse
SNX27-Mediated Recycling of Neuroligin-2 Regulates Inhibitory Signaling.Halff EF, Szulc BR, Lesept F, Kittler JT
Cell reports (2019) 299: 2599-2607.e6.
147 011 ICC; tested species: rat
HIV-1 Tat-Induced Astrocytic Extracellular Vesicle miR-7 Impairs Synaptic Architecture.Hu G, Niu F, Liao K, Periyasamy P, Sil S, Liu J, Dravid SM, Buch S
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology (2019) : .
147 011 WB, ICC, IHC; tested species: human,rat,monkey
Biallelic DMXL2 mutations impair autophagy and cause Ohtahara syndrome with progressive course.Esposito A, Falace A, Wagner M, Gal M, Mei D, Conti V, Pisano T, Aprile D, Cerullo MS, De Fusco A, Giovedì S, et al.
Brain : a journal of neurology (2019) : .
147 011 ICC; tested species: mouse
Regulation of dendrite morphology and excitatory synapse formation by zDHHC15.Shah BS, Shimell JJ, Bamji SX
Journal of cell science (2019) 13213: .
147 011 ICC; tested species: rat
The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation.Shimell JJ, Shah BS, Cain SM, Thouta S, Kuhlmann N, Tatarnikov I, Jovellar DB, Brigidi GS, Kass J, Milnerwood AJ, Snutch TP, et al.
Cell reports (2019) 298: 2422-2437.e8.
147 011 WB, ICC; tested species: rat
Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons.Marro SG, Chanda S, Yang N, Janas JA, Valperga G, Trotter J, Zhou B, Merrill S, Yousif I, Shelby H, Vogel H, et al.
Neuron (2019) 1034: 617-626.e6.
147 011 ICC; tested species: human
Essential role for InSyn1 in dystroglycan complex integrity and cognitive behaviors in mice.Uezu A, Hisey E, Kobayashi Y, Gao Y, Bradshaw TW, Devlin P, Rodriguiz R, Tata PR, Soderling S
eLife (2019) 8: .
147 011 ICC; tested species: mouse
Depolarizing, inhibitory GABA type A receptor activity regulates GABAergic synapse plasticity via ERK and BDNF signaling.Brady ML, Pilli J, Lorenz-Guertin JM, Das S, Moon CE, Graff N, Jacob TC
Neuropharmacology (2018) 128: 324-339.
147 011 ICC; tested species: rat
Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies.Dejanovic B, Huntley MA, De Mazière A, Meilandt WJ, Wu T, Srinivasan K, Jiang Z, Gandham V, Friedman BA, Ngu H, Foreman O, et al.
Neuron (2018) : .
147 011 ICC; tested species: mouse
Clptm1 Limits Forward Trafficking of GABAA Receptors to Scale Inhibitory Synaptic Strength.Ge Y, Kang Y, Cassidy RM, Moon KM, Lewis R, Wong ROL, Foster LJ, Craig AM
Neuron (2018) 973: 596-610.e8.
147 011 ICC, IHC; tested species: mouse
Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting.Awasthi A, Ramachandran B, Ahmed S, Benito E, Shinoda Y, Nitzan N, Heukamp A, Rannio S, Martens H, Barth J, Burk K, et al.
Science (New York, N.Y.) (2018) : .
147 011 ICC; tested species: rat
Prions activate a p38 MAPK synaptotoxic signaling pathway.Fang C, Wu B, Le NTT, Imberdis T, Mercer RCC, Harris DA
PLoS pathogens (2018) 149: e1007283.
147 011 ICC; tested species: mouse
GARLH Family Proteins Stabilize GABAA Receptors at Synapses.Yamasaki T, Hoyos-Ramirez E, Martenson JS, Morimoto-Tomita M, Tomita S
Neuron (2017) 935: 1138-1152.e6.
147 011 ICC
Alpha subunit-dependent glycine receptor clustering and regulation of synaptic receptor numbers.Patrizio A, Renner M, Pizzarelli R, Triller A, Specht CG
Scientific reports (2017) 71: 10899.
147 011 ICC; tested species: rat
Nanoscale Molecular Reorganization of the Inhibitory Postsynaptic Density Is a Determinant of GABAergic Synaptic Potentiation.Pennacchietti F, Vascon S, Nieus T, Rosillo C, Das S, Tyagarajan SK, Diaspro A, Del Bue A, Petrini EM, Barberis A, Cella Zanacchi F, et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017) 377: 1747-1756.
147 011 ICC
Adaptive-illumination STED nanoscopy.Heine J, Reuss M, Harke B, D'Este E, Sahl SJ, Hell SW
Proceedings of the National Academy of Sciences of the United States of America (2017) 11437: 9797-9802.
147 011 ICC; tested species: rat
Gephyrin-binding peptides visualize postsynaptic sites and modulate neurotransmission.Maric HM, Hausrat TJ, Neubert F, Dalby NO, Doose S, Sauer M, Kneussel M, Strømgaard K
Nature chemical biology (2017) 132: 153-160.
147 011 WB, ICC; tested species: mouse
Radixin regulates synaptic GABAA receptor density and is essential for reversal learning and short-term memory.Hausrat TJ, Muhia M, Gerrow K, Thomas P, Hirdes W, Tsukita S, Heisler FF, Herich L, Dubroqua S, Breiden P, Feldon J, et al.
Nature communications (2015) 6: 6872.
147 011 ICC
Super-Resolution Microscopy Reveals Presynaptic Localization of the ALS/FTD Related Protein FUS in Hippocampal Neurons.Schoen M, Reichel JM, Demestre M, Putz S, Deshpande D, Proepper C, Liebau S, Schmeisser MJ, Ludolph AC, Michaelis J, Boeckers TM, et al.
Frontiers in cellular neuroscience (2015) 9: 496.
147 011 ICC; tested species: rat
Plexin-B3 suppresses excitatory and promotes inhibitory synapse formation in rat hippocampal neurons.Laht P, Tammaru E, Otsus M, Rohtla J, Tiismus L, Veske A
Experimental cell research (2015) 3352: 269-78.
147 011 ICC
Activity-regulated trafficking of the palmitoyl-acyl transferase DHHC5.Brigidi GS, Santyr B, Shimell J, Jovellar B, Bamji SX
Nature communications (2015) 6: 8200.
147 011 ICC
Synaptic abnormalities and cytoplasmic glutamate receptor aggregates in contactin associated protein-like 2/Caspr2 knockout neurons.Varea O, Martin-de-Saavedra MD, Kopeikina KJ, Schürmann B, Fleming HJ, Fawcett-Patel JM, Bach A, Jang S, Peles E, Kim E, Penzes P, et al.
Proceedings of the National Academy of Sciences of the United States of America (2015) 11219: 6176-81.
147 011 ICC
A negative feedback loop controls NMDA receptor function in cortical interneurons via neuregulin 2/ErbB4 signalling.Vullhorst D, Mitchell RM, Keating C, Roychowdhury S, Karavanova I, Tao-Cheng JH, Buonanno A
Nature communications (2015) 6: 7222.
147 011 ICC
Proteomic analysis of glycine receptor β subunit (GlyRβ)-interacting proteins: evidence for syndapin I regulating synaptic glycine receptors.Del Pino I, Koch D, Schemm R, Qualmann B, Betz H, Paarmann I
The Journal of biological chemistry (2014) 28916: 11396-409.
147 011 ICC; tested species: rat
Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization.Wang SH, Celic I, Choi SY, Riccomagno M, Wang Q, Sun LO, Mitchell SP, Vasioukhin V, Huganir RL, Kolodkin AL
The Journal of neuroscience : the official journal of the Society for Neuroscience (2014) 3438: 12745-61.
147 011 ICC; tested species: mouse
Synaptic recruitment of gephyrin regulates surface GABAA receptor dynamics for the expression of inhibitory LTP.Petrini EM, Ravasenga T, Hausrat TJ, Iurilli G, Olcese U, Racine V, Sibarita JB, Jacob TC, Moss SJ, Benfenati F, Medini P, et al.
Nature communications (2014) 5: 3921.
147 011 ICC; tested species: mouse
Genetic evidence for the adhesion protein IgSF9/Dasm1 to regulate inhibitory synapse development independent of its intracellular domain.Mishra A, Traut MH, Becker L, Klopstock T, Stein V, Klein R
The Journal of neuroscience : the official journal of the Society for Neuroscience (2014) 3412: 4187-99.
147 011 ICC, IHC; tested species: mouse
High content image analysis identifies novel regulators of synaptogenesis in a high-throughput RNAi screen of primary neurons.Nieland TJ, Logan DJ, Saulnier J, Lam D, Johnson C, Root DE, Carpenter AE, Sabatini BL
PloS one (2014) 93: e91744.
147 011 ICC; tested species: mouse
Differential control of thrombospondin over synaptic glycine and AMPA receptors in spinal cord neurons.Hennekinne L, Colasse S, Triller A, Renner M
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3328: 11432-9.
147 011 ICC; tested species: rat
Quantitative nanoscopy of inhibitory synapses: counting gephyrin molecules and receptor binding sites.Specht CG, Izeddin I, Rodriguez PC, El Beheiry M, Rostaing P, Darzacq X, Dahan M, Triller A
Neuron (2013) 792: 308-21.
147 011 ICC; tested species: mouse
TNF-α downregulates inhibitory neurotransmission through protein phosphatase 1-dependent trafficking of GABA(A) receptors.Pribiag H, Stellwagen D
The Journal of neuroscience : the official journal of the Society for Neuroscience (2013) 3340: 15879-93.
147 011 ICC; tested species: rat
Effects of distinct collybistin isoforms on the formation of GABAergic synapses in hippocampal neurons.Körber C, Richter A, Kaiser M, Schlicksupp A, Mükusch S, Kuner T, Kirsch J, Kuhse J
Molecular and cellular neurosciences (2012) 503-4: 250-9.
147 011 ICC
Tracing synaptic connectivity onto embryonic stem cell-derived neurons.Garcia I, Huang L, Ung K, Arenkiel BR
Stem cells (Dayton, Ohio) (2012) 3010: 2140-51.
147 011 ICC; tested species: mouse
Molecular basis of the γ-aminobutyric acid A receptor α3 subunit interaction with the clustering protein gephyrin.Tretter V, Kerschner B, Milenkovic I, Ramsden SL, Ramerstorfer J, Saiepour L, Maric HM, Moss SJ, Schindelin H, Harvey RJ, Sieghart W, et al.
The Journal of biological chemistry (2011) 28643: 37702-11.
147 011 ICC; tested species: mouse
Astrocyte secreted proteins selectively increase hippocampal GABAergic axon length, branching, and synaptogenesis.Hughes EG, Elmariah SB, Balice-Gordon RJ
Molecular and cellular neurosciences (2010) 431: 136-45.
147 011 ICC; tested species: rat
Irregular RNA splicing curtails postsynaptic gephyrin in the cornu ammonis of patients with epilepsy.Förstera B, Belaidi AA, Jüttner R, Bernert C, Tsokos M, Lehmann TN, Horn P, Dehnicke C, Schwarz G, Meier JC
Brain : a journal of neurology (2010) 133Pt 12: 3778-94.
147 011 ICC
Induction of GABAergic postsynaptic differentiation by alpha-neurexins.Kang Y, Zhang X, Dobie F, Wu H, Craig AM
The Journal of biological chemistry (2008) 2834: 2323-34.
147 011 ICC; tested species: rat
Activity-dependent regulation of inhibitory synaptic transmission in hippocampal neurons.Hartman KN, Pal SK, Burrone J, Murthy VN
Nature neuroscience (2006) 95: 642-9.
147 011 ICC
Structure function and splice site analysis of the synaptogenic activity of the neurexin-1 beta LNS domain.Graf ER, Kang Y, Hauner AM, Craig AM
The Journal of neuroscience : the official journal of the Society for Neuroscience (2006) 2616: 4256-65.
147 011 ICC
Neuronal cotransport of glycine receptor and the scaffold protein gephyrin.Maas C, Tagnaouti N, Loebrich S, Behrend B, Lappe-Siefke C, Kneussel M
The Journal of cell biology (2006) 1723: 441-51.
147 011 ICC
Gephyrin regulates the cell surface dynamics of synaptic GABAA receptors.Jacob TC, Bogdanov YD, Magnus C, Saliba RS, Kittler JT, Haydon PG, Moss SJ
The Journal of neuroscience : the official journal of the Society for Neuroscience (2005) 2545: 10469-78.
147 011 ICC
A gephyrin-related mechanism restraining glycine receptor anchoring at GABAergic synapses.Meier J, Grantyn R
The Journal of neuroscience : the official journal of the Society for Neuroscience (2004) 246: 1398-405.
147 011 ICC
GSK3 and KIF5 regulate activity-dependent sorting of gephyrin between axons and dendrites.Rathgeber L, Gromova KV, Schaefer I, Breiden P, Lohr C, Kneussel M
European journal of cell biology () 943-4: 173-8.
147 011 ICC