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Home > Products > 141 111AbRED

Bassoon antibody - 141 111AbRED K.O.

Bassoon is a large multi-domain protein of the presynaptic active zone
Mouse monoclonal purified IgG
Cat. No.: 141 111AbRED
Amount: 100 µg
Price: $465.00
Cat. No. 141 111AbRED 100 µg purified IgG, lyophilized, fluorescence-labeled with abberior STAR RED.

abberior STAR® dyes have been especially developed for for Stimulated Emission Depletion (STED) microscopy which allows higher resolution imaging compared to confocal laser scanning microscopy. For many of the fluorescence labeled antibodies conjugated to abberior STAR® dyes established fluorescence detection systems can be used.

abberior STAR® 635P: λex 638 nm / λem 651 nm
abberior STAR® ORANGE: λex 589 nm / λem 616 nm
abberior STAR® RED: λex 638 nm / λem 655 nm
 

This product or portions thereof is manufactured under license from abberior GmbH.
abberior STAR is a trademark of abberior GmbH, Goettingen/Germany.
Purchase of reagents related to the abberior STAR technology from Synaptic Systems GmbH provides a license for non-profit and in-house research use only. Any application of above mentioned technology for commercial purpose requires a separate license from abberior GmbH.

 Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Either add 1:1 (v/v) glycerol, then aliquot and store at -20°C until use, or store aliquots at -80°C without additives.
Reconstitute immediately upon receipt! Avoid bright light when working with the antibody to minimize photo bleeching of the fluorescent dye.
Applications
 
WB: N/A
IP: N/A
ICC: 1 : 300 (see remarks) gallery  
IHC: not tested yet
IHC-P: not tested yet
Label abberior STAR RED
Clone 179H11A2
Subtype IgG2a (κ light chain)
Immunogen Recombinant protein corresponding to residues near the central region of rat Bassoon (UniProt Id: O88778)
Reactivity Reacts with: mouse (O88737), rat (O88778).
Other species not tested yet.
Specificity K.O. validated
Remarks

ICC: This antibody conjugate is especially suitable for high resolution STED microscopy.
Data sheet 141_111abred.pdf
Cat. No.: 141 111AbRED
Amount: 100 µg
Price: $465.00
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Background

Bassoon is a large protein which consists of an N-terminal Zn2+ finger and several piccolo-bassoon homology domains (PBH-domains). It is generally found together with piccolo, a related huge multi-domain protein of the CAZ (cytoskeletal matrix assembled at active zones).
Bassoon was suggested to be a scaffolding element of the presynapse but deletion experiments in mice have shown that bassoon is also involved in synaptic vesicle cycling. Probably bassoon interacts with other protein factors via its Zn2+ domain but the potential partners have not been determined yet.
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