Cat. No.: 111 203BT
Amount: 50 µg
Price:
$480.00
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| Cat. No. 111 203BT |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen, labeled with Biotin.
Biotin is a small vitamin B complex molecule. Its small size minimizes interference with antibody binding sites and allows for efficient conjugation without compromising antibody functionality. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications |
IP: yes (see remarks) ICC: not tested yet IHC: not tested yet IHC-P: not tested yet |
| Label | biotin |
| Immunogen | Synthetic peptide corresponding to AA 196 to 211 from human SNAP23 (UniProt Id: O00161) |
| Reactivity |
Reacts with: rat (O70377), mouse (O09044). Other species not tested yet. |
| Matching control protein/peptide | 111-2P |
| Remarks |
IP: Antibody 2 (cat. no. 111 213) is recommended. |
| Data sheet | 111_203bt.pdf |
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SNAP23 (synaptosome-associated protein of 23 kDa) is an ubiquitously expressed isoform and functional homologue of SNAP25. It is resistant to cleavage by BoNT/A and E. The protein is part of the exocytotic fusion complex (v-SNARE) where it assembles with syntaxin1 and synaptobrevin.
SNAP23 is able to function in regulated exocytosis. Both isoforms may have their own specific binding partners and discrete, albeit mechanistically similar, functional roles within the cell.