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Home > Products > 110 072

Syntaxin7 antibody - 110 072 K.D.

Syntaxin7 is a SNARE protein involved in endosomal and lysosomal fusion reactions
Rabbit polyclonal antiserum
Cat. No.: 110 072
Amount: 200 µl
Price: $355.00
Cat. No. 110 072 200 µl antiserum, lyophilized. For reconstitution add 200 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 up to 1 : 5000 (AP staining) gallery  
IP: yes
ICC: 1 : 100 gallery  
IHC: yes
IHC-P: 1 : 200 gallery  

Western blot (WB); separation of proteins by PAGE and subsequent transfer to a membrane. Detection of target molecules is carried out with antibodies. Some antibodies require special sample preparation steps. For details, please refer to the “Remarks” section.

Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section.

Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section.

Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section.

Immunohistochemistry (IHC-P) of formalin fixed, paraffin embedded (FFPE) tissue (some antibodies require special antigen retrieval steps, please refer to the ”Remarks” section). Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate.
Immunogen Recombinant protein corresponding to AA 1 to 236 from rat Syntaxin7 (UniProt Id: O70257)
Reactivity Reacts with: human (O15400), rat (O70257), mouse (O70439).
Other species not tested yet.
Specificity K.D. validated PubMed: 17389686
Matching control protein/peptide 110-7P
Data sheet 110_072.pdf

References for Syntaxin7 - 110 072

Cardiac SNARE Expression in Health and Disease.
Bowman PRT, Smith GL, Gould GW
Frontiers in endocrinology (2019) 10: 881. 110 072 WB; tested species: mouse
Salmonella SipA mimics a cognate SNARE for host Syntaxin8 to promote fusion with early endosomes.
Singh PK, Kapoor A, Lomash RM, Kumar K, Kamerkar SC, Pucadyil TJ, Mukhopadhyay A
The Journal of cell biology (2018) : . 110 072 WB, ICC; tested species: human
Oxidized phagosomal NOX2 complex is replenished from lysosomes.
Dingjan I, Linders PT, van den Bekerom L, Baranov MV, Halder P, Ter Beest M, van den Bogaart G
Journal of cell science (2017) 1307: 1285-1298. 110 072 WB, IP, ICC; KD verified; tested species: human
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Wilhelm BG, Mandad S, Truckenbrodt S, Kröhnert K, Schäfer C, Rammner B, Koo SJ, Claßen GA, Krauss M, Haucke V, Urlaub H, et al.
Science (New York, N.Y.) (2014) 3446187: 1023-8. 110 072 WB, ICC, IHC
Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins.
Amessou M, Fradagrada A, Falguières T, Lord JM, Smith DC, Roberts LM, Lamaze C, Johannes L
Journal of cell science (2007) 120Pt 8: 1457-68. 110 072 WB; KD verified; tested species: human
Modification of host lipid raft proteome upon hepatitis C virus replication.
Mannová P, Fang R, Wang H, Deng B, McIntosh MW, Hanash SM, Beretta L
Molecular & cellular proteomics : MCP (2006) 512: 2319-25. 110 072 WB
Molecular anatomy of a trafficking organelle.
Takamori S, Holt M, Stenius K, Lemke EA, Grønborg M, Riedel D, Urlaub H, Schenck S, Brügger B, Ringler P, Müller SA, et al.
Cell (2006) 1274: 831-46. 110 072 WB
High-throughput identification of IMCD proteins using LC-MS/MS.
Pisitkun T, Bieniek J, Tchapyjnikov D, Wang G, Wu WW, Shen RF, Knepper MA
Physiological genomics (2006) 252: 263-76. 110 072 WB
Association of ABCA1 with syntaxin 13 and flotillin-1 and enhanced phagocytosis in tangier cells.
Bared SM, Buechler C, Boettcher A, Dayoub R, Sigruener A, Grandl M, Rudolph C, Dada A, Schmitz G
Molecular biology of the cell (2004) 1512: 5399-407. 110 072 WB
Rab3D is not required for exocrine exocytosis but for maintenance of normally sized secretory granules.
Riedel D, Antonin W, Fernandez-Chacon R, Alvarez de Toledo G, Jo T, Geppert M, Valentijn JA, Valentijn K, Jamieson JD, Südhof TC, Jahn R, et al.
Molecular and cellular biology (2002) 2218: 6487-97. 110 072 WB
A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function.
Antonin W, Holroyd C, Fasshauer D, Pabst S, Von Mollard GF, Jahn R
The EMBO journal (2000) 1923: 6453-64. 110 072 WB
Oxidized phagosomal NOX2 complex is replenished from lysosomes.
Dingjan I, Linders PT, van den Bekerom L, Baranov MV, Halder P, Ter Beest M, van den Bogaart G
Journal of cell science (2017) 1307: 1285-1298. 110 072 WB, IP, ICC; KD verified; tested species: human
Syntaxin 6 and Vti1b form a novel SNARE complex, which is up-regulated in activated macrophages to facilitate exocytosis of tumor necrosis Factor-alpha.
Murray RZ, Wylie FG, Khromykh T, Hume DA, Stow JL
The Journal of biological chemistry (2005) 28011: 10478-83. 110 072 IP
Salmonella SipA mimics a cognate SNARE for host Syntaxin8 to promote fusion with early endosomes.
Singh PK, Kapoor A, Lomash RM, Kumar K, Kamerkar SC, Pucadyil TJ, Mukhopadhyay A
The Journal of cell biology (2018) : . 110 072 WB, ICC; tested species: human
Oxidized phagosomal NOX2 complex is replenished from lysosomes.
Dingjan I, Linders PT, van den Bekerom L, Baranov MV, Halder P, Ter Beest M, van den Bogaart G
Journal of cell science (2017) 1307: 1285-1298. 110 072 WB, IP, ICC; KD verified; tested species: human
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Wilhelm BG, Mandad S, Truckenbrodt S, Kröhnert K, Schäfer C, Rammner B, Koo SJ, Claßen GA, Krauss M, Haucke V, Urlaub H, et al.
Science (New York, N.Y.) (2014) 3446187: 1023-8. 110 072 WB, ICC, IHC
SNARE protein expression and localization in human cytotoxic T lymphocytes.
Pattu V, Qu B, Schwarz EC, Strauss B, Weins L, Bhat SS, Halimani M, Marshall M, Rettig J, Hoth M
European journal of immunology (2012) 422: 470-5. 110 072 ICC
Expression and function of neuronal growth-associated proteins (nGAPs) in PC12 cells.
Lu J, Nozumi M, Takeuchi K, Abe H, Igarashi M
Neuroscience research (2011) 701: 85-90. 110 072 ICC
A VAMP7/Vti1a SNARE complex distinguishes a non-conventional traffic route to the cell surface used by KChIP1 and Kv4 potassium channels.
Flowerdew SE, Burgoyne RD
The Biochemical journal (2009) 4183: 529-40. 110 072 ICC
Mammalian ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain.
Hasegawa H, Zinsser S, Rhee Y, Vik-Mo EO, Davanger S, Hay JC
Molecular biology of the cell (2003) 142: 698-720. 110 072 ICC
Proteomic analysis reveals the composition of glutamatergic organelles of auditory inner hair cell.
Cepeda AP, Ninov M, Neef J, Parfentev I, Kusch K, Reisinger E, Jahn R, Moser T, Urlaub H
Molecular & cellular proteomics : MCP (2023) : 100704. 110 072 IHC; tested species: mouse
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Wilhelm BG, Mandad S, Truckenbrodt S, Kröhnert K, Schäfer C, Rammner B, Koo SJ, Claßen GA, Krauss M, Haucke V, Urlaub H, et al.
Science (New York, N.Y.) (2014) 3446187: 1023-8. 110 072 WB, ICC, IHC
Cat. No.: 110 072
Amount: 200 µl
Price: $355.00
Cardiac SNARE Expression in Health and Disease.
Bowman PRT, Smith GL, Gould GW
Frontiers in endocrinology (2019) 10: 881. 110 072 WB; tested species: mouse
Salmonella SipA mimics a cognate SNARE for host Syntaxin8 to promote fusion with early endosomes.
Singh PK, Kapoor A, Lomash RM, Kumar K, Kamerkar SC, Pucadyil TJ, Mukhopadhyay A
The Journal of cell biology (2018) : . 110 072 WB, ICC; tested species: human
Oxidized phagosomal NOX2 complex is replenished from lysosomes.
Dingjan I, Linders PT, van den Bekerom L, Baranov MV, Halder P, Ter Beest M, van den Bogaart G
Journal of cell science (2017) 1307: 1285-1298. 110 072 WB, IP, ICC; KD verified; tested species: human
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Wilhelm BG, Mandad S, Truckenbrodt S, Kröhnert K, Schäfer C, Rammner B, Koo SJ, Claßen GA, Krauss M, Haucke V, Urlaub H, et al.
Science (New York, N.Y.) (2014) 3446187: 1023-8. 110 072 WB, ICC, IHC
Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins.
Amessou M, Fradagrada A, Falguières T, Lord JM, Smith DC, Roberts LM, Lamaze C, Johannes L
Journal of cell science (2007) 120Pt 8: 1457-68. 110 072 WB; KD verified; tested species: human
Modification of host lipid raft proteome upon hepatitis C virus replication.
Mannová P, Fang R, Wang H, Deng B, McIntosh MW, Hanash SM, Beretta L
Molecular & cellular proteomics : MCP (2006) 512: 2319-25. 110 072 WB
Molecular anatomy of a trafficking organelle.
Takamori S, Holt M, Stenius K, Lemke EA, Grønborg M, Riedel D, Urlaub H, Schenck S, Brügger B, Ringler P, Müller SA, et al.
Cell (2006) 1274: 831-46. 110 072 WB
High-throughput identification of IMCD proteins using LC-MS/MS.
Pisitkun T, Bieniek J, Tchapyjnikov D, Wang G, Wu WW, Shen RF, Knepper MA
Physiological genomics (2006) 252: 263-76. 110 072 WB
Association of ABCA1 with syntaxin 13 and flotillin-1 and enhanced phagocytosis in tangier cells.
Bared SM, Buechler C, Boettcher A, Dayoub R, Sigruener A, Grandl M, Rudolph C, Dada A, Schmitz G
Molecular biology of the cell (2004) 1512: 5399-407. 110 072 WB
Rab3D is not required for exocrine exocytosis but for maintenance of normally sized secretory granules.
Riedel D, Antonin W, Fernandez-Chacon R, Alvarez de Toledo G, Jo T, Geppert M, Valentijn JA, Valentijn K, Jamieson JD, Südhof TC, Jahn R, et al.
Molecular and cellular biology (2002) 2218: 6487-97. 110 072 WB
A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function.
Antonin W, Holroyd C, Fasshauer D, Pabst S, Von Mollard GF, Jahn R
The EMBO journal (2000) 1923: 6453-64. 110 072 WB
Oxidized phagosomal NOX2 complex is replenished from lysosomes.
Dingjan I, Linders PT, van den Bekerom L, Baranov MV, Halder P, Ter Beest M, van den Bogaart G
Journal of cell science (2017) 1307: 1285-1298. 110 072 WB, IP, ICC; KD verified; tested species: human
Syntaxin 6 and Vti1b form a novel SNARE complex, which is up-regulated in activated macrophages to facilitate exocytosis of tumor necrosis Factor-alpha.
Murray RZ, Wylie FG, Khromykh T, Hume DA, Stow JL
The Journal of biological chemistry (2005) 28011: 10478-83. 110 072 IP
Salmonella SipA mimics a cognate SNARE for host Syntaxin8 to promote fusion with early endosomes.
Singh PK, Kapoor A, Lomash RM, Kumar K, Kamerkar SC, Pucadyil TJ, Mukhopadhyay A
The Journal of cell biology (2018) : . 110 072 WB, ICC; tested species: human
Oxidized phagosomal NOX2 complex is replenished from lysosomes.
Dingjan I, Linders PT, van den Bekerom L, Baranov MV, Halder P, Ter Beest M, van den Bogaart G
Journal of cell science (2017) 1307: 1285-1298. 110 072 WB, IP, ICC; KD verified; tested species: human
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Wilhelm BG, Mandad S, Truckenbrodt S, Kröhnert K, Schäfer C, Rammner B, Koo SJ, Claßen GA, Krauss M, Haucke V, Urlaub H, et al.
Science (New York, N.Y.) (2014) 3446187: 1023-8. 110 072 WB, ICC, IHC
SNARE protein expression and localization in human cytotoxic T lymphocytes.
Pattu V, Qu B, Schwarz EC, Strauss B, Weins L, Bhat SS, Halimani M, Marshall M, Rettig J, Hoth M
European journal of immunology (2012) 422: 470-5. 110 072 ICC
Expression and function of neuronal growth-associated proteins (nGAPs) in PC12 cells.
Lu J, Nozumi M, Takeuchi K, Abe H, Igarashi M
Neuroscience research (2011) 701: 85-90. 110 072 ICC
A VAMP7/Vti1a SNARE complex distinguishes a non-conventional traffic route to the cell surface used by KChIP1 and Kv4 potassium channels.
Flowerdew SE, Burgoyne RD
The Biochemical journal (2009) 4183: 529-40. 110 072 ICC
Mammalian ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain.
Hasegawa H, Zinsser S, Rhee Y, Vik-Mo EO, Davanger S, Hay JC
Molecular biology of the cell (2003) 142: 698-720. 110 072 ICC
Proteomic analysis reveals the composition of glutamatergic organelles of auditory inner hair cell.
Cepeda AP, Ninov M, Neef J, Parfentev I, Kusch K, Reisinger E, Jahn R, Moser T, Urlaub H
Molecular & cellular proteomics : MCP (2023) : 100704. 110 072 IHC; tested species: mouse
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins.
Wilhelm BG, Mandad S, Truckenbrodt S, Kröhnert K, Schäfer C, Rammner B, Koo SJ, Claßen GA, Krauss M, Haucke V, Urlaub H, et al.
Science (New York, N.Y.) (2014) 3446187: 1023-8. 110 072 WB, ICC, IHC
WB
ICC
IHC-P
Background

Syntaxin 7, a member of the SNARE family of proteins, is related to syntaxins 1-4 but localized to endosomal membranes of a wide variety of cells.
Syntaxin 7 is involved in the fusion of late endosomes and lysosomes. In endosomal membranes, it forms complexes with endobrevin, syntaxin 8 and vti1b.
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