EHD2 regulates plasma membrane integrity and downstream insulin receptor signalling events.Neuhaus M, Fryklund C, Taylor H, Borreguero-Muñoz A, Kopietz F, Ardalani H, Rogova O, Stirrat L, Bremner SK, Spégel P, Bryant NJ, et al.
Molecular biology of the cell (2023) : mbcE23030078.
110 042 WB, ICC; tested species: mouse
EFR3 and phosphatidylinositol 4-kinase IIIα regulate insulin-stimulated glucose transport and GLUT4 dispersal in 3T3-L1 adipocytes.Koester AM, Geiser A, Laidlaw KME, Morris S, Cutiongco MFA, Stirrat L, Gadegaard N, Boles E, Black HL, Bryant NJ, Gould GW, et al.
Bioscience reports (2022) 427: .
110 042 WB; tested species: mouse
Diabetes is accompanied by changes in the levels of proteins involved in endosomal GLUT4 trafficking in obese human skeletal muscle.Livingstone R, Bryant NJ, Boyle JG, Petrie JR, Gould GW
Endocrinology, diabetes & metabolism (2022) 55: e361.
110 042 WB; tested species: human
Knockout of Syntaxin-4 in 3T3-L1 adipocytes reveals new insight into GLUT4 trafficking and adiponectin secretion.Black HL, Livingstone R, Mastick CC, Al Tobi M, Taylor H, Geiser A, Stirrat L, Kioumourtzoglou D, Petrie JR, Boyle JG, Bryant NJ, et al.
Journal of cell science (2021) : .
110 042 WB; KO verified; tested species: mouse
Pancreas-specific SNAP23 depletion prevents pancreatitis by attenuating pathological basolateral exocytosis and formation of trypsin-activating autolysosomes.Dolai S, Takahashi T, Qin T, Liang T, Xie L, Kang F, Miao YF, Xie H, Kang Y, Manuel J, Winter E, et al.
Autophagy (2020) : 1-14.
110 042 WB, IP; tested species: human
Invasion by activated macrophages requires delivery of nascent MT1-MMP through late endosomes/lysosomes to the cell surface.Röhl J, West ZE, Rudolph M, Zaharia A, Van Lonkhuyzen D, Hickey DK, Semmler ABT, Murray RZ
Traffic (Copenhagen, Denmark) (2019) : .
110 042 WB, ICC; tested species: mouse
Cardiac SNARE Expression in Health and Disease.Bowman PRT, Smith GL, Gould GW
Frontiers in endocrinology (2019) 10: 881.
110 042 WB; tested species: mouse
Depletion of the membrane-fusion regulator Munc18c attenuates caerulein hyperstimulation-induced pancreatitis.Dolai S, Liang T, Orabi AI, Xie L, Holmyard D, Javed TA, Fernandez NA, Xie H, Cattral MS, Thurmond DC, Thorn P, et al.
The Journal of biological chemistry (2018) 2937: 2510-2522.
110 042 WB, IP; tested species: mouse
Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium.Zhang S, Lebreton F, Mansfield MJ, Miyashita SI, Zhang J, Schwartzman JA, Tao L, Masuyer G, Martínez-Carranza M, Stenmark P, Gilmore MS, et al.
Cell host & microbe (2018) 232: 169-176.e6.
110 042 WB; tested species: mouse
Limited proteolysis as a tool to probe the tertiary conformation of dysferlin and structural consequences of patient missense variant L344P.Woolger N, Bournazos A, Sophocleous RA, Evesson FJ, Lek A, Driemer B, Sutton RB, Cooper ST
The Journal of biological chemistry (2017) 29245: 18577-18591.
110 042 WB; tested species: human
Insulin stimulates syntaxin4 SNARE complex assembly via a novel regulatory mechanism.Kioumourtzoglou D, Gould GW, Bryant NJ
Molecular and cellular biology (2014) 347: 1271-9.
110 042 ICC, WB
Tumor protein D52 controls trafficking of an apical endolysosomal secretory pathway in pancreatic acinar cells.Messenger SW, Thomas DD, Falkowski MA, Byrne JA, Gorelick FS, Groblewski GE
American journal of physiology. Gastrointestinal and liver physiology (2013) 3056: G439-52.
110 042 WB; tested species: rat
Legionella pneumophila promotes functional interactions between plasma membrane syntaxins and Sec22b.Arasaki K, Roy CR
Traffic (Copenhagen, Denmark) (2010) 115: 587-600.
110 042 WB, ICC; tested species: human
Role of insulin-dependent cortical fodrin/spectrin remodeling in glucose transporter 4 translocation in rat adipocytes.Liu L, Jedrychowski MP, Gygi SP, Pilch PF
Molecular biology of the cell (2006) 1710: 4249-56.
110 042 ICC, WB; tested species: rat
