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Home > Products > 110 041

Syntaxin4 antibody - 110 041

Syntaxin4 is an ubiquitous plasma membrane protein involved in fusion of vesicles with the plasma membrane
Mouse monoclonal purified IgG
Cat. No.: 110 041
Amount: 100 µg
Price: $415.00
Cat. No. 110 041 100 µg purified IgG, lyophilized. Albumin and azide were added for stabilization. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: yes
ICC: 1 : 100 gallery  
IHC: not recommended
IHC-P: not tested yet

Western blot (WB); separation of proteins by PAGE and subsequent transfer to a membrane. Detection of target molecules is carried out with antibodies. Some antibodies require special sample preparation steps. For details, please refer to the “Remarks” section.

Immunoprecipitation (IP); Immunoisolation or pulldown of a target molecule using an antibody. For details and product specific hints, please refer to the ”Remarks” section.

Immunocytochemistry (ICC) on 4% PFA fixed cells. Immunoreactivity is usually revealed by fluorescence. Some antibodies require special fixation methods. For details, please refer to the “Remarks” section.

Immunohistochemistry (IHC) on 4% PFA perfusion fixed tissue with 24h PFA post fixation. Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate. Some antibodies require special fixation methods or antigen retrieval steps. For details, please refer to the ”Remarks” section.

Immunohistochemistry (IHC-P) of formalin fixed, paraffin embedded (FFPE) tissue (some antibodies require special antigen retrieval steps, please refer to the ”Remarks” section). Immunoreactivity is usually revealed by fluorescence or a chromogenic substrate.
Clone 139.2
Subtype IgG1 (κ light chain)
Immunogen Recombinant protein corresponding to AA 1 to 273 from rat Syntaxin4 (UniProt Id: Q08850)
Reactivity Reacts with: rat (Q08850), mouse (P70452).
No signal: zebrafish.
Other species not tested yet.
Matching control protein/peptide 110-4P
Data sheet 110_041.pdf

References for Syntaxin4 - 110 041

Deletion of murine astrocytic vesicular nucleotide transporter increases anxiety and depressive-like behavior and attenuates motivation for reward.
Huang Q, Lee HH, Volpe B, Zhang Q, Xue C, Liu BC, Abuhasan YR, Li L, Yang JS, Egholm J, Gutierrez-Vazquez C, et al.
Molecular psychiatry (2024) : . 110 041 WB; tested species: mouse
Dendritic autophagy degrades postsynaptic proteins and is required for long-term synaptic depression in mice.
Kallergi E, Daskalaki AD, Kolaxi A, Camus C, Ioannou E, Mercaldo V, Haberkant P, Stein F, Sidiropoulou K, Dalezios Y, Savitski MM, et al.
Nature communications (2022) 131: 680. 110 041 WB; tested species: mouse
Tomosyn regulates the small RhoA GTPase to control the dendritic stability of neurons and the surface expression of AMPA receptors.
Shen W, Kilander MBC, Bridi MS, Frei JA, Niescier RF, Huang S, Lin YC
Journal of neuroscience research (2020) : . 110 041 WB, IP; tested species: mouse
A trap mutant reveals the physiological client spectrum of TRC40.
Coy-Vergara J, Rivera-Monroy J, Urlaub H, Lenz C, Schwappach B
Journal of cell science (2019) 13213: . 110 041 WB; tested species: human
Tomosyn regulates the small RhoA GTPase to control the dendritic stability of neurons and the surface expression of AMPA receptors.
Shen W, Kilander MBC, Bridi MS, Frei JA, Niescier RF, Huang S, Lin YC
Journal of neuroscience research (2020) : . 110 041 WB, IP; tested species: mouse
LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells.
Trepte P, Kruse S, Kostova S, Hoffmann S, Buntru A, Tempelmeier A, Secker C, Diez L, Schulz A, Klockmeier K, Zenkner M, et al.
Molecular systems biology (2018) 147: e8071. 110 041 ICC; tested species: mouse
Hydrophobic mismatch sorts SNARE proteins into distinct membrane domains.
Milovanovic D, Honigmann A, Koike S, Göttfert F, Pähler G, Junius M, Müllar S, Diederichsen U, Janshoff A, Grubmüller H, Risselada HJ, et al.
Nature communications (2015) 6: 5984. 110 041 ICC
Cat. No.: 110 041
Amount: 100 µg
Price: $415.00
Deletion of murine astrocytic vesicular nucleotide transporter increases anxiety and depressive-like behavior and attenuates motivation for reward.
Huang Q, Lee HH, Volpe B, Zhang Q, Xue C, Liu BC, Abuhasan YR, Li L, Yang JS, Egholm J, Gutierrez-Vazquez C, et al.
Molecular psychiatry (2024) : . 110 041 WB; tested species: mouse
Dendritic autophagy degrades postsynaptic proteins and is required for long-term synaptic depression in mice.
Kallergi E, Daskalaki AD, Kolaxi A, Camus C, Ioannou E, Mercaldo V, Haberkant P, Stein F, Sidiropoulou K, Dalezios Y, Savitski MM, et al.
Nature communications (2022) 131: 680. 110 041 WB; tested species: mouse
Tomosyn regulates the small RhoA GTPase to control the dendritic stability of neurons and the surface expression of AMPA receptors.
Shen W, Kilander MBC, Bridi MS, Frei JA, Niescier RF, Huang S, Lin YC
Journal of neuroscience research (2020) : . 110 041 WB, IP; tested species: mouse
A trap mutant reveals the physiological client spectrum of TRC40.
Coy-Vergara J, Rivera-Monroy J, Urlaub H, Lenz C, Schwappach B
Journal of cell science (2019) 13213: . 110 041 WB; tested species: human
Tomosyn regulates the small RhoA GTPase to control the dendritic stability of neurons and the surface expression of AMPA receptors.
Shen W, Kilander MBC, Bridi MS, Frei JA, Niescier RF, Huang S, Lin YC
Journal of neuroscience research (2020) : . 110 041 WB, IP; tested species: mouse
LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells.
Trepte P, Kruse S, Kostova S, Hoffmann S, Buntru A, Tempelmeier A, Secker C, Diez L, Schulz A, Klockmeier K, Zenkner M, et al.
Molecular systems biology (2018) 147: e8071. 110 041 ICC; tested species: mouse
Hydrophobic mismatch sorts SNARE proteins into distinct membrane domains.
Milovanovic D, Honigmann A, Koike S, Göttfert F, Pähler G, Junius M, Müllar S, Diederichsen U, Janshoff A, Grubmüller H, Risselada HJ, et al.
Nature communications (2015) 6: 5984. 110 041 ICC
WB
ICC
Background

Syntaxin 4, a member of the SNARE family of proteins, is related to syntaxin 1. Like syntaxin 2 it is predominantly localized to the plasma membrane of a wide variety of cells. Similar to syntaxins 1, 2, and 3, it appears to be involved in the fusion of transport vesicles with the plasma membrane.
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