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Synaptotagmin2 antibody luminal domain - 105 224

Synaptotagmin2 is an alternative Ca2+-sensor for neurotransmitter release
Guinea pig polyclonal antiserum
Cat. No.: 105 224
Amount: 100 µl
Price: $365.00
Cat. No. 105 224 100 µl antiserum, lyophilized. For reconstitution add 100 µl H2O, then aliquot and store at -20°C until use.
Antibodies should be stored at +4°C when still lyophilized. Do not freeze!
Applications
 
WB: 1 : 1000 (AP staining) gallery  
IP: not tested yet
ICC: 1 : 500 gallery  
IHC: not recommended
IHC-P: not tested yet
Immunogen Synthetic peptide corresponding to AA 1 to 11 from mouse Synaptotagmin2 (UniProt Id: P46097)
Reactivity Reacts with: mouse (P46097), rat (P29101).
Other species not tested yet.
Data sheet 105_224.pdf
Cat. No.: 105 224
Amount: 100 µl
Price: $365.00
Background

Synaptotagmin2 is an integral membrane glycoprotein of neuronal synaptic vesicles. It is very similar to synaptotagmin1 but shows a partly complementary expression pattern in the CNS. Synaptotagmin2 lacks a CAMK II/PKC phosphorylation site which is present in synaptotagmin1.
Recently synaptotagmin2 has been shown to be an alternative Ca2+ sensor for fast secretion.