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Cat. No. 102 005 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
Applications | |
Immunogen | Synthetic peptide corresponding to AA 250 to 265 from rat Synaptoporin (UniProt Id: P22831) |
Reactivity |
Reacts with: rat (P22831), mouse (Q8BGN8), hamster. Other species not tested yet. |
Matching control protein/peptide | 102-0P |
Remarks |
WB: Less powerful compared to the rabbit antibodies (102 002 and 102 003). |
Data sheet | 102_005.pdf |
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Synaptoporin, also known as synaptophysin2 and p38-2, is highly homologous to synaptophysin1 but encoded by a different gene. Like synaptopysin1, synaptoporin contains four transmembrane regions and a short cytoplasmic tail. Unlike synaptophysin1, it is not glycosylated.
The distributions of synaptophysin1 and synaptoporin are different. Synaptophysin1 is more uniformly expressed whereas synaptoporin is particularly enriched in mossy fiber synapses in the hippocampus. It is thus an excellent marker for subsets of synapses.