Cat. No.: 102-1P
Amount: 100 µg
Price:
$110.00
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| Cat. No. 102-1P |
100 µg peptide, lyophilized. For reconstitution add 100 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Control peptides should be stored at -20°C when still lyophilized! |
| Applications |
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| Immunogen | Synthetic peptide corresponding to residues near the carboxy terminus of rat Synaptoporin (UniProt Id: P22831) |
| Matching antibodies | 102 002, 102 003, 102 011, 102 008, 102 308 |
| Remarks |
This control peptide consists of the synthetic peptide (aa 250 to 263 from rat Synaptoporin) that has been used for immunization. It has been tested in preadsorption experiments and blocks efficiently and specifically the corresponding signal in Western blots. The amount of peptide needed for efficient blocking depends on the titer and on the affinity of the antibody to the antigen. |
| Data sheet | 102-1p.pdf |
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Synaptoporin, also known as synaptophysin2 and p38-2, is highly homologous to synaptophysin1 but encoded by a different gene. Like synaptopysin1, synaptoporin contains four transmembrane regions and a short cytoplasmic tail. Unlike synaptophysin1, it is not glycosylated.
The distributions of synaptophysin1 and synaptoporin are different. Synaptophysin1 is more uniformly expressed whereas synaptoporin is particularly enriched in mossy fiber synapses in the hippocampus. It is thus an excellent marker for subsets of synapses.